Download or read book Direitos Humanos written by Ivete Manetzeder Keil and published by . This book was released on 2002 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Great Granny Webster written by Caroline Blackwood and published by New York Review of Books. This book was released on 2012-04-18 with total page 129 pages. Available in PDF, EPUB and Kindle. Book excerpt: Shortlisted for the Booker Prize The real-life Guinness heiress offers an inside look at the lives of eccentric aristocrats in this “masterful . . . macabre fairy-tale and blackly humorous family portrait” (Literary Hub). This macabre, mordantly funny, partly auto-biographical novel reveals the gothic craziness behind the scenes in the great houses of the aristocracy, as witnessed through the unsparing eyes of an orphaned teenage girl. Great Granny Webster herself is a fabulous monster, the chilliest of matriarchs, presiding with steely self-regard over a landscape of ruined lives. Great Granny Webster is Caroline Blackwood’s masterpiece. Heiress to the Guinness fortune, Blackwood was celebrated as a great beauty and dazzling raconteur long before she made her name as a strikingly original writer.
Download or read book Innovation in Pharmacy Advances and Perspectives September 2018 written by Organizer Committee IPAP18 – Salamanca and published by Ediciones Universidad de Salamanca. This book was released on 2018-09-21 with total page 358 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book contains the summaries of the "Innovation in Pharmacy: Advances and Perspectives" that took place in Salamanca (Spain) in September 2018. The early science of chemistry and microbiology were the source of most drugs until the revolution of genetic engineering in the mid 1970s. Then biotechnology made available novel protein agents such as interferons, blood factors and monoclonal antibodies that have changed the modern pharmacy. Over the past year, a new pharmacy of oligonucleotides has emerged from the science of gene expression such as RNA splicing and RNA interference. The ability to design therapeutic agents from genomic sequences will transform treatment for many diseases. The science that created this advance and its future promise will be discussed. Phillip Allen Sharp is an American geneticist and molecular biologist who co-discovered RNA splicing. He shared the 1993 Nobel Prize in Physiology or Medicine with Richard J. Roberts for “the discovery that genes in eukaryotes are not contiguous strings but contain introns, and that the splicing of messenger RNA to delete those introns can occur in different ways, yielding different proteins from the same DNA sequence. He works in Institute Professor Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology (MIT), Cambridge, MA, US. Este libro recoge los resúmenes de la «Innovation in Pharmacy: Advances and Perspectives» que tuvo lugar en Salamanca (España) en septiembre de 2018. La ciencia primitiva de la química y la microbiología fue la fuente de la mayoría de las drogas hasta la revolución de la ingeniería genética a mediados de la década de 1970. Luego, la biotecnología puso a disposición agentes proteínicos novedosos como interferones, factores sanguíneos y anticuerpos monoclonales que han cambiado la farmacia moderna. Durante el año pasado, surgió una nueva farmacia de oligonucleótidos a partir de la ciencia de la expresión génica, como el empalme de ARN y la interferencia de ARN. La capacidad de diseñar agentes terapéuticos a partir de secuencias genómicas transformará el tratamiento de muchas enfermedades. La ciencia que creó este avance y su promesa futura será discutida. Phillip Allen Sharp es un genetista y biólogo molecular estadounidense que co-descubrió el empalme de ARN. Compartió el Premio Nobel de 1993 en Fisiología o Medicina con Richard J. Roberts por "el descubrimiento de que los genes en eucariotas no son cadenas contiguas, sino que contienen intrones, y que el empalme del ARN mensajero para eliminar esos intrones puede ocurrir de diferentes maneras, produciendo diferentes proteínas de la misma secuencia de ADN. Trabaja en el Instituto Profesor Koch Institute for Integrative Cancer Research, Instituto Tecnológico de Massachusetts (MIT), Cambridge, MA, EE. UU.
Download or read book Brazil and the Emergence of a Digital Lusosphere written by Valnora Leister and published by Rowman & Littlefield. This book was released on 2018-09-15 with total page 225 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book maps how Brazil and the network of Portuguese-speaking countries—the “Lusosphere”—are using digital technologies in new ways to expand opportunities at all levels of society. From a diverse range of perspectives across the Portuguese-speaking world, contributors to this volume explore such questions as the capability of information technologies to encourage social inclusion in the face of economic inequality, the kinds of cultural values that may replace those of the scarcity-based industrial era, and the potential emergence of a virtual world order based on soft power, given the failures of hard power alternatives. This book explores how digital linkages between Brazil and physically-separated Portuguese-speaking communities are influencing the arts, creative industries, sports, learning, business, and cultural evolution for hundreds of millions of Portuguese-speaking people on five continents. At a time of escalating calls in Europe and North America to close borders and build walls, Brazil and the Emergence of a Digital Lusosphere charts alternatives that offer inspiration and practical paths toward a more inclusive world.
Download or read book Doutoramento Honoris Causa de Jorge Sampaio written by Imprensa da Universidade de Coimbra and published by Imprensa da Universidade de Coimbra / Coimbra University Press. This book was released on 2010-01-01 with total page 98 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nada fornecido
Download or read book Proceedings of the Conference written by Inter-American Bar Association and published by . This book was released on 1943 with total page 1392 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Ontological Security in International Relations written by Brent J. Steele and published by Routledge. This book was released on 2008-03-10 with total page 257 pages. Available in PDF, EPUB and Kindle. Book excerpt: The central assertion of this book is that states pursue social actions to serve self-identity needs, even when these actions compromise their physical existence. Three forms of social action, sometimes referred to as ‘motives’ of state behaviour (moral, humanitarian, and honour-driven) are analyzed here through an ontological security approach. Brent J. Steele develops an account of social action which interprets these behaviours as fulfilling a nation-state's drive to secure self-identity through time. The anxiety which consumes all social agents motivates them to secure their sense of being, and thus he posits that transformational possibilities exist in the ‘Self’ of a nation-state. The volume consequently both challenges and complements realist, liberal, constructivist and post-structural accounts to international politics. Using ontological security to interpret three cases - British neutrality during the American Civil War (1861-1865), Belgium’s decision to fight Germany in 1914, and NATO’s (1999) Kosovo intervention - the book concludes by discussing the importance for self-interrogation in both the study and practice of international relations. Ontological Security in International Relations will be of particular interest to students and researchers of international politics, international ethics, international relations and security studies.
Download or read book Inclusion Matters written by World Bank and published by World Bank Publications. This book was released on 2013-11-26 with total page 302 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report tries to put boundaries around the abstraction that is "social inclusion". It is intended for policy makers, academics, activists and development partners - indeed anyone who is curious about how to address inclusion in a world that is witness to intense demographic, spatial, economic and technological transitions. Placing the discussion of social inclusion within such global transitions and transformations, it argues that social inclusion is an evolving agenda. While it does not purport to provide definitive answers as to how to achieve social inclusion in any given context, the report offers an easy-to-use definition and a framework to assist practitioners in asking, outlining and developing some of the right questions that can help advance the agenda of inclusion in different contexts. There are seven main messages in this report: 1. Excluded groups exist in all countries. 2. Excluded groups are consistently denied opportunities. 3. Intense global transitions are leading to social transformations that create new opportunities for inclusion as well as exacerbating existing forms of exclusion. 4. People take part in society through markets, services, and spaces. 5. Social and economic transformations affect the attitudes and perceptions of people. As people act on the basis of how they feel, it is important to pay attention to their attitudes and perceptions. 6. Exclusion is not immutable. Abundant evidence demonstrates that social inclusion can be planned and achieved. 7. Moving ahead will require a broader and deeper knowledge of exclusion and its impacts as well as taking concerted action.
Download or read book A grande refazenda written by and published by . This book was released on 2007 with total page 128 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Translational Medicine written by Joy A. Cavagnaro and published by CRC Press. This book was released on 2021-11-26 with total page 952 pages. Available in PDF, EPUB and Kindle. Book excerpt: Translational Medicine: Optimizing Preclinical Safety Evaluation of Biopharmaceuticals provides scientists responsible for the translation of novel biopharmaceuticals into clinical trials with a better understanding of how to navigate the obstacles that keep innovative medical research discoveries from becoming new therapies or even making it to clinical trials. The book includes sections on protein-based therapeutics, modified proteins, oligonucleotide-based therapies, monoclonal antibodies, antibody–drug conjugates, gene and cell-based therapies, gene-modified cell-based therapies, combination products, and therapeutic vaccines. Best practices are defined for efficient discovery research to facilitate a science-based, efficient, and predictive preclinical development program to ensure clinical efficacy and safety. Key Features: Defines best practices for leveraging of discovery research to facilitate a development program Includes general principles, animal models, biomarkers, preclinical toxicology testing paradigms, and practical applications Discusses rare diseases Discusses "What-Why-When-How" highlighting different considerations based upon product attributes. Includes special considerations for rare diseases About the Editors Joy A. Cavagnaro is an internationally recognized expert in preclinical development and regulatory strategy with an emphasis on genetic medicines.. Her 40-year career spans academia, government (FDA), and the CRO and biotech industries. She was awarded the 2019 Arnold J Lehman Award from the Society of Toxicology for introducing the concept of science-based, case-by-case approach to preclinical safety evaluation, which became the foundation of ICH S6. She currently serves on scientific advisory boards for advocacy groups and companies and consults and lectures in the area of preclinical development of novel therapies. Mary Ellen Cosenza is a regulatory toxicology consultant with over 30 years of senior leadership experience in the biopharmaceutical industry in the U.S., Europe, and emerging markets. She has held leadership position in both the American College of Toxicology (ACT) and the International Union of Toxicology (IUTOX) and is also an adjunct assistant professor at the University of Southern California where she teaches graduate-level courses in toxicology and regulation of biologics.
Download or read book Curso de Derecho Internacional written by and published by . This book was released on 1989 with total page 194 pages. Available in PDF, EPUB and Kindle. Book excerpt: Supplements accompany some issues.
Download or read book Globaliza o written by Roland Robertson and published by . This book was released on 2000 with total page 316 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Capitulos written by and published by . This book was released on 2001 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Bolet n Mensual de la Oficina de Las Rep blicas Americanas Inion Internacional de Rep blicas Americanas written by and published by . This book was released on 1905 with total page 1038 pages. Available in PDF, EPUB and Kindle. Book excerpt:
