Download or read book A New Route to the Synthesis of Organic Phosphorus Compounds written by Warren Leon Jensen and published by . This book was released on 1948 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Phosphorus Ylides written by Oleg I. Kolodiazhnyi and published by John Wiley & Sons. This book was released on 2008-09-26 with total page 568 pages. Available in PDF, EPUB and Kindle. Book excerpt: When Wittig first developed and described phosphorus ylides, nobody could have imagined how useful and versatile this class of compounds could be. This book provides a comprehensive and up-to-date compilation of the chemistry and applications of phosphorus ylides in organic synthesis. The ylides are discussed as reagents in the synthesis of a broad range of substances, amongst them olefins, acetylenes, cyclic and heterocyclic compounds, in such naturally occurring compounds as pheromones, steroids and carotenoids, and pharmaceutically and biologically active compounds such as antibiotics and prostaglandins. A particularly beneficial feature of this book is the 150 key experimental procedures with all the necessary data, allowing the preparation to start immediately without the need for an extremely time-consuming literature search. But should a search prove inevitable, around 2,500 references provide easy access to the primary literature. Every chemist in academia and industry working in organic, bioorganic, inorganic, and medicinal chemistry will welcome this book as an inspiration of concepts, ideas and practical syntheses.
Download or read book The Synthesis of Organic Phosphorus Compounds written by T. Henshall and published by . This book was released on 1941 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Synthesis of Carbon Phosphorus Bonds written by Robert Engel and published by CRC Press. This book was released on 2003-12-18 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt: Synthesis of Carbon-Phosphorus Bonds, Second Edition is a working guide for the laboratory, incorporating classical approaches with the recent developments of carbon-phosphorus (C-P) bond formation. These advances include the preparation of phosphoranes - specifically in the use of transient oxophosphoranes as intermediates in organophosphorus comp
Download or read book Abstracts of Dissertations for the Degrees of Doctor of Philosophy and Doctor of Education written by Stanford University and published by . This book was released on 1948 with total page 1266 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Synthesis and Properties of Organic Compounds Containing Phosphorus and Silicon written by Edward Chang and published by . This book was released on 1963 with total page 176 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Development of Phosphorus Mediated Reactions in Organic Synthesis Y Xia Xuanshu B SC Sun Yat Sen U written by Xuanshu Xia and published by Open Dissertation Press. This book was released on 2017-01-27 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: This dissertation, "Development of phosphorus-mediated reactions in organic synthesis / y Xia Xuanshu, B. Sc., Sun Yat-sen U" by Xuanshu, Xia, 夏轩庶, was obtained from The University of Hong Kong (Pokfulam, Hong Kong) and is being sold pursuant to Creative Commons: Attribution 3.0 Hong Kong License. The content of this dissertation has not been altered in any way. We have altered the formatting in order to facilitate the ease of printing and reading of the dissertation. All rights not granted by the above license are retained by the author. Abstract: Polymer-supported catalysts and reagents have been widely used in organic chemistry because they could facilitate the purification procedures and usually be recycled. Much research has been directed to polymer-supported catalysts and reagents, mainly focusing on these aspects, such as new polymer support, new application in organic chemistry, different modifications and so on. Many polymer-supported phosphine reagents have been developed for Wittig reaction. However, most of them suffer from swelling issue or low loading. A new polyethlyeneimine-supported triphenylphosphine has been synthesized and used as a highly loaded bifunctional homogeneous reagent in a range of one-pot Wittig reactions. All the substrates afforded desired products in high yields after only simple purification procedures. Furthermore, it also served efficiently in reaction cascades involving a one-pot Wittig reaction followed by conjugate reduction of alkene products. In these transformations the phosphine oxide generated in Wittig reaction served as the catalyst for activating trichlorosilane in the subsequent reduction reaction. Triphenylphosphine oxide is always considered as a byproduct of Wittig and Mitsunobu reactions which complicates the purification procedures. One option to utilize it is its application in halogenation reaction with oxalyl halide. Heterogeneous polymer-supported triphenylphosphine oxides based on the rasta resin architecture have been synthesized, and applied as reagent precursors in a wide range of halogenation reactions. The rasta resin-triphenylphosphine oxides reacted with either oxalyl chloride or oxalyl bromide to form the corresponding halophosphonium salts, and these in turn reacted with alcohols, aldehydes, aziridines and epoxides to form halogenated products in high yields after simple purification. The polymer-supported triphenylphosphine oxides formed as a byproduct during these reactions could be recovered and reused numerous times with no appreciable decrease in reactivity. Another option is to use triphenylphosphine oxide as catalyst in organic synthesis. A highly regioselective 1,4-reduction of conjugated polyunsaturated ketones catalyzed by triphenylphosphine oxide is described. In the presence of triphenylphosphine oxide, conjugated di-, tri-, and tetraenones were selectively α,β-reduced using trichlorosilane without over reduction or isomerization, and all the substrates rendered desired products in high yields. Furthermore, 1,4-reduction products were successfully obtained in sequential one-pot Wittig/conjugate reduction reaction, triphenylphosphine oxide generated in Wittig reaction served as the catalyst for reduction reaction. In addition, natural moth pheromones and their analogues were synthesized in high yields using this method. Finally, the synthesis of γ-sanshool and hydroxy-γ-sanshool is depicted. The synthetic route started from simple and commercially available building blocks using an alkyne for E, E-2,4-diene group of the key synthetic intermediate 2E,4E,8Z,10E,12E-tetradecapentaenoic acid, which in turn was converted into both γ-sanshool and hydroxy-γ-sanshool by reaction with the appropriate amines. DOI: 10.5353/th_b5435655 Subjects: Supported reagents Polymers
Download or read book Synthesis of Carbon Phosphorus Bonds Second Edition written by Robert Engel and published by CRC Press. This book was released on 2003-12-18 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt: Synthesis of Carbon-Phosphorus Bonds, Second Edition is a working guide for the laboratory, incorporating classical approaches with the recent developments of carbon-phosphorus (C-P) bond formation. These advances include the preparation of phosphoranes - specifically in the use of transient oxophosphoranes as intermediates in organophosphorus compound synthesis ñ along with the new approaches towards the preparation of compounds with aromatic and vinylic C-P bonds. Synthesis of Carbon-Phosphorus Bonds, Second Edition serves as a useful tool in the laboratory. It offers detailed surveys of IUPAC nomenclature recommendations, common notation systems, and various experimental examples. These features help to make this text an effective source of critical and annotated references, as well as a a working guide for organic and phosphorus chemists specifically, or for any chemists working with C-P bonds.
Download or read book Abstracts of Dissertations for the Degrees of Doctor of Philosophy and Doctor of Education with the Titles of Theses Accepted for the Degrees of Engineer Master of Arts and Master of Science written by Stanford University and published by . This book was released on 1950 with total page 1264 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Organophosphorus Chemistry written by David W Allen and published by Royal Society of Chemistry. This book was released on 2007-10-31 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: Organophosphorus Chemistry provides a comprehensive annual review of the literature. Coverage includes phosphines and their chalcogenides, phosphonium salts, low coordination number phosphorus compounds, penta- and hexa-coordinated compounds, tervalent phosphorus acids, nucleotides and nucleic acids, ylides and related compounds, and phosphazenes. The series will be of value to research workers in universities, government and industrial research organisations, whose work involves the use of organophosphorus compounds. It provides a concise but comprehensive survey of a vast field of study with a wide variety of applications, enabling the reader to rapidly keep abreast of the latest developments in their specialist areas. Specialist Periodical Reports provide systematic and detailed review coverage of progress in the major areas of chemical research. Written by experts in their specialist fields the series creates a unique service for the active research chemist, supplying regular critical in-depth accounts of progress in particular areas of chemistry. For over 80 years the Royal Society of Chemistry and its predecessor, the Chemical Society, have been publishing reports charting developments in chemistry, which originally took the form of Annual Reports. However, by 1967 the whole spectrum of chemistry could no longer be contained within one volume and the series Specialist Periodical Reports was born. The Annual Reports themselves still existed but were divided into two, and subsequently three, volumes covering Inorganic, Organic and Physical Chemistry. For more general coverage of the highlights in chemistry they remain a 'must'. Since that time the SPR series has altered according to the fluctuating degree of activity in various fields of chemistry. Some titles have remained unchanged, while others have altered their emphasis along with their titles; some have been combined under a new name whereas others have had to be discontinued. The current list of Specialist Periodical Reports can be seen on the inside flap of this volume.
Download or read book Reactivity of P H Group of Phosphorus Based Compounds written by Kolio D. Troev and published by Academic Press. This book was released on 2017-09-06 with total page 465 pages. Available in PDF, EPUB and Kindle. Book excerpt: Reactivity of P-H Group of Phosphorus Based Compounds bridges the gap between inorganic and organic phosphorus compounds, providing a basis to explore the myriad possibilities for synthesis of novel low and high molecular phosphorus-containing compounds. It covers well-documented reactions in detail, including: tautomerization, oxidation, reduction, alkylation, oxidation coupling, addition reaction to: carbon-carbon multiple bonds, Schiff base, isocyanates, nitriles, epoxides; addition to carbonyl group, Kabachnik- Fields reaction, cross-coupling reaction and more. In an accessible style complete with synthetic routes and figures, the resource then covers the reactivity of multiple P-H group members: phosphines, phosphine oxides, hypophosphorus acid, H-phosphinic acids and polys(alkylene H-phosphonate). This valuable coverage supports the advancement of research and applications in this area for scientists solving a scientific problem or starting a variety of new projects, such as a new reaction for the synthesis of biologically active compounds, new methods of polymer synthesis or a new methodology for polymer modification. Describes the diverse reactivity of the phosphorus-hydrogen group, perhaps the most powerful in organic chemistry Includes practical information for the synthesis of catalysts, biologically active substances, flame retardants, advance materials and polymer materials Offers a visually-accessible guide to important reactions by an internationally recognized chemist
Download or read book New Methodologies for the Synthesis of Chiral Phosphorus Acids and Related Compounds written by Karen Winters (Chemist) and published by . This book was released on 2021 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Organocatalysis has become a major subdiscipline in (asymmetric) organic synthesis. Among chiral organocatalysts, C2-symmetrical chiral phosphorus acids (CPAs) occupy a rather special place because they can catalyze numerous transformations as Brønsted acids, however, they suffer from serious limitations such as: extremely high cost (they are much too expensive for use on an industrial scale, and often too expensive even on much smaller academic scales), very high molecular weight, inability to access both enantiomers without a significant and separate synthetic effort, difficulty in catalyst-immobilization, etc. In order to solve these problems, which hamper the broader uses and applications of CPAs, our proposed approach is to rely on compounds in which the phosphorus atom is chiral (called P-stereogenic, P-chiral, or P-chirogenic) but the rest of the molecule is not. This dissertation presents our development and research findings for the synthesis of chiral phosphorus acids as well as their application in asymmetric organocatalysis.
Download or read book Doctoral Dissertations Accepted by American Universities written by Donald Bean Gilchrist and published by . This book was released on 1949 with total page 202 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Handbook of Organophosphorus Chemistry written by Robert Engel and published by CRC Press. This book was released on 1992-06-19 with total page 896 pages. Available in PDF, EPUB and Kindle. Book excerpt: This practical work summarizes the development of organophosphorus chemistry in topical areas and details the discipline's current state - providing applications and experimental procedures throughout.;Written by 18 leading authorities in the field, the Handbook of Organophosphorus Chemistry: examines advances in the mechanistic understanding of th
Download or read book New Reactions and Reagents for Phosphorus carbon Bond formation written by Michael B. Geeson and published by . This book was released on 2020 with total page 373 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chapter 1 takes the format of an "Outlook", and sets forth the case for developing sustainable methods in the synthesis of phosphorus-containing compounds. Methods used by nature for phosphorus-carbon bond-formation, or in the chemistry of other elements such as silicon, are discussed as model processes for the future of phosphorus in chemical synthesis. Chapter 2 describes the discovery of [TBA][P(SiCl3)2], prepared from [TBA]3[P3O9]-.2H2O and trichlorosilane. The bis(trichlorosilyl)phosphide anion is used to prepare compounds that contain P–C, P–O, P–F, and P–H bonds in a method that bypasses white phosphorus (P4), the traditional route to organophosphorus compounds. Chapter 3 extends the phosphate precursors to [TBA][P(SiCl3)2] from trimetaphosphate to crystalline phosphoric acid. Balanced equations are developed for the formation of [TBA][P(SiCl3)2] from phosphate sources and the byproducts are identified as hexachlorodisiloxane and hydrogen gas. Extension of trichlorosilane reduction to bisulfate provides improved access the known trichlorosilylsulfide anion, [TBA][SSiCl3]. This anion was used as a thionation reagent to prepare thiobenzophenone and benzyl mercaptan from benzophenone and benzyl bromide, respectively. Chapter 4 describes the synthesis of neutral phosphine, HP(SiCl3)2, obtained by protonation of [TBA]1 with triflic acid. HP(SiCl3)2 is a highly efficient reagent for photochemical hydrophosphination of terminal alkenes. The phosphorus-silicon bonds in the hydrophosphination products can be functionalized to provide compounds of the general formulae: RPCl2, RPH2, [RP(R')3]Cl, RP(O)(H)(OH), and RP(O)(OH)2. Chapter 5 describes a method to prepare phosphiranes (three-membered rings that contain a phosphorus atom) from anthracene-based phosphinidene precursors and styrenic olefins. The phosphinidene transfer reaction requires an organoiron and fluoride catalyst. The resulting phosphirane is prepared in good yield (73%) with high stereoselectivity (>99%). Experimental investigations into the mechanism point toward the intermediacy of an iron-coordinated fluorophosphide species.
Download or read book Organophosphorus Chemistry 2018 written by György Keglevich and published by MDPI. This book was released on 2020-03-05 with total page 602 pages. Available in PDF, EPUB and Kindle. Book excerpt: Organophosphorus chemistry is an important discipline within organic chemistry. Phosphorus compounds, such as phosphines, trialkyl phosphites, phosphine oxides (chalcogenides), phosphonates, phosphinates and >P(O)H species, etc., may be important starting materials or intermediates in syntheses. Let us mention the Wittig reaction and the related transformations, the Arbuzov- and the Pudovik reactions, the Kabachnik–Fields condensation, the Hirao reaction, the Mitsunobu reaction, etc. Other reactions, e.g., homogeneous catalytic transformations or C-C coupling reactions involve P-ligands in transition metal (Pt, Pd, etc.) complex catalysts. The synthesis of chiral organophosphorus compounds means a continuous challenge. Methods have been elaborated for the resolution of tertiary phosphine oxides and for stereoselective organophosphorus transformations. P-heterocyclic compounds, including aromatic and bridged derivatives, P-functionalized macrocycles, dendrimers and low coordinated P-fragments, are also of interest. An important segment of organophosphorus chemistry is the pool of biologically-active compounds that are searched and used as drugs, or as plant-protecting agents. The natural analogue of P-compounds may also be mentioned. Many new phosphine oxides, phosphinates, phosphonates and phosphoric esters have been described, which may find application on a broad scale. Phase transfer catalysis, ionic liquids and detergents also have connections to phosphorus chemistry. Green chemical aspects of organophosphorus chemistry (e.g., microwave-assisted syntheses, solvent-free accomplishments, optimizations, and atom-efficient syntheses) represent a dynamically developing field. Last, but not least, theoretical approaches and computational chemistry are also a strong sub-discipline within organophosphorus chemistry.
Download or read book Synthesis of Silicon Nitrogen Phosphorus Compounds Including a New Synthesis of Phosphazenes written by Robert H. Neilson and published by . This book was released on 1979 with total page 5 pages. Available in PDF, EPUB and Kindle. Book excerpt: This research under ARO sponsorship has been directed toward the synthesis, characterization, structural isomerization, and thermal decomposition reactions of new silicon-nitrogen-phosphorus compounds. Some of these compounds undergo smooth decomposition when heated to afford phosphazenes, oligomeric materials of general formula (NPRR')n.
