Download or read book A Multimodal Breast Cancer Imaging System Using Coregistered Dynamic Diffuse Optical Tomography and Digital Breast Tomosynthesis written by Bernhard B. Zimmermann and published by . This book was released on 2017 with total page 102 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diffuse optical tomography (DOT) is an emerging noninvasive functional imaging method for breast cancer diagnosis and neoadjuvant chemotherapy monitoring. In particular, the multimodal approach of combining DOT with x-ray digital breast tomosynthesis (DBT) is especially synergistic as DBT prior information can be used to enhance the DOT reconstruction. DOT, in turn, provides a functional information overlay onto the mammographic images, increasing sensitivity and specificity to cancer pathology. We describe a dynamic DOT apparatus designed for tight integration with commercial DBT scanners and providing a fast (1 Hz+) image acquisition rate to enable tracking of hemodynamic changes induced by the mammographic breast compression. The most significant advance enabling fast acquisition was the design and construction of a direct analog-to-digital conversion frequency-domain near-infrared spectroscopy (FD-NIRS) component. It achieves simultaneous dual wavelength operation at 685 nm and 830 nm by concurrent 67.5 MHz and 75 MHz frequency modulation of each laser source, respectively, followed by digitization using a high-speed analog to digital converter and real-time hybrid FPGA-assisted demodulation by discrete Fourier transform (DFT). The overall DOT system integrates 96 CW-NIRS and 24 FD-NIRS source locations, as well as 32 CW-NIRS and 20 FD-NIRS detection locations into low-profile plates that mate to the DBT compression paddle and x-ray detector cover, respectively. The plates and the embedded optical fibers are made of plastic to minimize x-ray absorption and thus allow true simultaneous acquisition of the DBT image. We first characterize each major system component individually, and then demonstrate overall performance using static and dynamic tissue-like phantoms, as well as in vivo images acquired from the pool of patients recalled for breast biopsies at the Massachusetts General Hospital Breast Imaging Division.
Download or read book Digital Breast Tomosynthesis written by Alberto Tagliafico and published by Springer. This book was released on 2016-05-03 with total page 156 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive description of the screening and clinical applications of digital breast tomosynthesis (DBT) and offers straightforward, clear guidance on use of the technique. Informative clinical cases are presented to illustrate how to take advantage of DBT in clinical practice. The importance of DBT as a diagnostic tool for both screening and diagnosis is increasing rapidly. DBT improves upon mammography by depicting breast tissue on a video clip made of cross‐sectional images reconstructed in correspondence with their mammographic planes of acquisition. DBT results in markedly reduced summation of overlapping breast tissue and offers the potential to improve mammographic breast cancer surveillance and diagnosis. This book will be an excellent practical teaching guide for beginners and a useful reference for more experienced radiologists.
Download or read book Optical Molecular Imaging in Cancer Research written by Guanglei Zhang and published by Frontiers Media SA. This book was released on 2022-04-20 with total page 201 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Breast Tomosynthesis E Book written by Liane E Philpotts and published by Elsevier Health Sciences. This book was released on 2016-11-02 with total page 267 pages. Available in PDF, EPUB and Kindle. Book excerpt: The use of tomosynthesis in breast imaging is growing rapidly due to its superior ability to identify and characterize normal findings, benign lesions, and breast cancer, as well as its optimal performance with dense breast tissue. Providing unparalleled coverage of this breakthrough breast imaging modality, Breast Tomosynthesis explains how this new modality can lead to enhanced interpretation and better patient outcomes. This new reference is an indispensable guide for today's practitioner looking to keep abreast of the latest developments with correlative findings, practical interpretation tips, physics, and information on how tomosynthesis differs from conventional 2D FFDM mammography. Over 900 high-quality images offer visual guidance to effectively reading and interpreting this key imaging modality. - Includes over 900 high-quality tomosynthesis and mammography images representing the spectrum of breast imaging. - Features the latest Breast Imaging Reporting and Data System (or BI-RADS) standards updated in February 2014. - Highlights practical tips to interpreting this new modality and how it differs from 2D mammography. - Details how integration of tomosynthesis drastically changes lesion work-up and overall workflow in the department. - "Tomo Tips" boxes offer tips and pitfalls for expert clinical guidance.
Download or read book Atlas of Breast Tomosynthesis written by Martin Sonnenschein and published by Springer. This book was released on 2017-06-08 with total page 558 pages. Available in PDF, EPUB and Kindle. Book excerpt: This superbly illustrated atlas of breast tomosynthesis covers all aspects and applications of the technology, which reduces tissue overlap and facilitates the recognition of small cancers. After clear explanation of basic principles of the technique, individual chapters address diagnostic criteria, indications, and use of breast tomosynthesis as a screening tool. The findings obtained in the full range of benign and malignant conditions, including postoperative changes, are then presented with the aid of a wealth of high-quality illustrations from case examples. Detailed attention is paid to the BI-RADS classification, bearing in mind the ability of tomosynthesis to reduce categorizations as BI-RADS 3 and 0, thereby decreasing the recall rate. The book concludes by examining tomosynthesis-guided interventions such as vacuum-assisted breast biopsy and galactography.
Download or read book Clinical Breast Tomosynthesis written by Lonie R. Salkowski and published by Thieme. This book was released on 2017-08-03 with total page 2123 pages. Available in PDF, EPUB and Kindle. Book excerpt: Case studies provide a stellar resource for mastering clinical breast tomosynthesis technology Digital breast tomosynthesis (DBT), popularly called "3D mammography" is a state-of-the-art breast imaging technology that provides the ability to view inside the breast, layer by layer. Advantages of DBT include elimination of superimposed tissue, improved detection of otherwise hidden lesions, and significantly higher cancer detection rates compared to conventional mammography. Although it is increasingly being implemented in imaging centers, hands-on clinical learning tools have been lacking - until now. Written by renowned breast imaging specialists, this multimedia textbook is the most definitive DBT reference available. The first section is dedicated to DBT fundamentals, including physics, reconstruction methods, acquisition parameters, and patient dose and data size considerations. The next two sections are case-based clinical practice presentations, organized by DBT screening and diagnostic components. Key Features The use of 3D breast imaging to detect and differentiate malignancies from normal and benign findings 100 case studies include pertinent clinical information, introductory images, and findings labeled on subsequent images with BI-RADS terminology Full field digital mammography and/or synthetic 2D mammogram images included in all case studies mirror what is typically encountered in DBT breast-imaging programs Clinical pearls on navigating the technology, interpreting images, making diagnoses, and decisions regarding follow-up studies Accompanying online videos further elucidate the still images This remarkable, interactive reference is a must-have for trainee and practicing radiologists and will also benefit mammography technicians. The detailed case studies and videos demonstrate the full utility of DBT as a screening and diagnostic technology in context with mammography, ultrasound, and MRI of the breast.
Download or read book Physics of Mammographic Imaging written by Mia K. Markey and published by CRC Press. This book was released on 2012-11-09 with total page 321 pages. Available in PDF, EPUB and Kindle. Book excerpt: Due to the increasing number of digital mammograms and the advent of new kinds of three-dimensional x-ray and other forms of medical imaging, mammography is undergoing a dramatic change. To meet their responsibilities, medical physicists must constantly renew their knowledge of advances in medical imaging or radiation therapy, and must be prepared to function at the intersection of these two fields. Physics of Mammographic Imaging gives an overview on the current role and future potential of new alternatives to mammography in the context of clinical need, complementary approaches, and ongoing research. This book provides comprehensive coverage on the fundamentals of image formation, image interpretation, analysis, and modeling. It discusses the use of mammographic imaging in the detection, diagnosis, treatment planning, and monitoring of breast cancer. Expert authors give a balanced summary of core topics such as digital mammography, contrast-enhanced mammography, stereomammography, breast tomosynthesis, and breast CT. The book highlights the use of mammographic imaging with complementary breast imaging modalities such as ultrasound, MRI, and nuclear medicine techniques. It discusses critical issues such as computer-aided diagnosis, perception, and quality assurance. This is an exciting time in the development of medical imaging, with many new technologies poised to make a substantial impact on breast cancer care. This book will help researchers and students get up to speed on crucial developments and contribute to future advances in the field.
Download or read book Digital Breast Tomosynthesis written by Joerg Barkhausen and published by Thieme. This book was released on 2015-10-20 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt: Digital Breast Tomosynthesis: Technique and Cases is a comprehensive and timely introduction to a significant technological advance in breast cancer imaging. This state-of-the-art guide explains the technique of digital breast tomosynthesis (DBT), describes results from available clinical studies, offers recommendations for the use of DBT in routine practice, and discusses the latest developments and possible future trends in DBT. The main part of the book contains 45 highly illustrated case reports that allow readers to explore the practical aspects of DBT and deepen their knowledge of this important new modality in breast imaging. Key Features: Presents 45 superbly illustrated case reports showcasing the application of DBT to clinical practice Examines the results of all currently available clinical trials and studies Evaluates the use of DBT alongside mammography and versus mammography Includes high-quality images from the various modalities in breast imaging: 2D mammography, DBT, and ultrasound, to enable comparison of their strengths and limitations Combines expertise in the fields of radiology and gynecology with an interdisciplinary team of contributors Provides video clips of the DBT data set for most cases on the Thieme MediaCenter Authoritative and up to date, this volume is essential for radiology practitioners, residents, and fellows who wish to learn about the potential of DBT and stay at the forefront of technological developments in their field. The wealth of clinically relevant information is useful for any radiologist considering the establishment of DBT as a new imaging tool in their practice.
Download or read book Digital Mammography written by Ulrich Bick and published by Springer Science & Business Media. This book was released on 2010-03-11 with total page 222 pages. Available in PDF, EPUB and Kindle. Book excerpt: Digital Radiography has been ? rmly established in diagnostic radiology during the last decade. Because of the special requirements of high contrast and spatial resolution needed for roentgen mammography, it took some more time to develop digital m- mography as a routine radiological tool. Recent technological progress in detector and screen design as well as increased ex- rience with computer applications for image processing have now enabled Digital Mammography to become a mature modality that opens new perspectives for the diag- sis of breast diseases. The editors of this timely new volume Prof. Dr. U. Bick and Dr. F. Diekmann, both well-known international leaders in breast imaging, have for many years been very active in the frontiers of theoretical and translational clinical research, needed to bring digital mammography ? nally into the sphere of daily clinical radiology. I am very much indebted to the editors as well as to the other internationally rec- nized experts in the ? eld for their outstanding state of the art contributions to this v- ume. It is indeed an excellent handbook that covers in depth all aspects of Digital Mammography and thus further enriches our book series Medical Radiology. The highly informative text as well as the numerous well-chosen superb illustrations will enable certi? ed radiologists as well as radiologists in training to deepen their knowledge in modern breast imaging.
Download or read book Mammography and Beyond written by National Research Council and published by National Academies Press. This book was released on 2001-07-23 with total page 311 pages. Available in PDF, EPUB and Kindle. Book excerpt: Each year more than 180,000 new cases of breast cancer are diagnosed in women in the U.S. If cancer is detected when small and local, treatment options are less dangerous, intrusive, and costly-and more likely to lead to a cure. Yet those simple facts belie the complexity of developing and disseminating acceptable techniques for breast cancer diagnosis. Even the most exciting new technologies remain clouded with uncertainty. Mammography and Beyond provides a comprehensive and up-to-date perspective on the state of breast cancer screening and diagnosis and recommends steps for developing the most reliable breast cancer detection methods possible. This book reviews the dramatic expansion of breast cancer awareness and screening, examining the capabilities and limitations of current and emerging technologies for breast cancer detection and their effectiveness at actually reducing deaths. The committee discusses issues including national policy toward breast cancer detection, roles of public and private agencies, problems in determining the success of a technique, availability of detection methods to specific populations of women, women's experience during the detection process, cost-benefit analyses, and more. Examining current practices and specifying research and other needs, Mammography and Beyond will be an indispensable resource to policy makers, public health officials, medical practitioners, researchers, women's health advocates, and concerned women and their families.
Download or read book A Diffuse Optical Tomography System Combined with X ray Mammography for Improved Breast Cancer Detection written by Thomas John Brukilacchio and published by . This book was released on 2003 with total page 440 pages. Available in PDF, EPUB and Kindle. Book excerpt: The central thesis of this dissertation states that optical imaging of diffuse tissues must be combined in co-registration with a recognized gold standard of mammographic screening, i.e. X-ray mammography, to gain wide acceptance in the clinical environment. This multi-modality imaging approach promises to overcome the deficiencies of both imaging modalities by drawing on the strengths of each. Functional and structural image contrast would be provided by optical and high-resolution structural contrast by X-ray. Furthermore, the structural information provided by X-ray could be used to improve the optical image reconstruction by providing boundary information and soft constraints for weakly correlated structural contrast. Ultimately, image-processing techniques could be developed to provide the radiologist with a three-dimensional image indicative of both optical and X-ray contrast that would provide much greater information content than either modality alone.
Download or read book Breast Imaging written by Andrew D.A. Maidment and published by Springer. This book was released on 2012-07-13 with total page 804 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the refereed proceedings of the 11th International Workshop on Digital Mammography, IWDM 2012, held in Philadelphia, PA, USA, in July 2012. The 42 revised full papers and 58 revised poster papers presented were carefully reviewed and selected from numerous initial submissions. The papers are organized in topical sections on contrast-enhancing imaging, digital mammography methods, tomosynthesis system design, tomosynthesis - image quality and dose, clinical tomosynthesis, functional breast imaging, breast computed tomography, computer-aided diagnosis and image processing, tomosynthesis reconstruction, and breast density.
Download or read book Alternative Breast Imaging written by Keith D. Paulsen and published by Springer Science & Business Media. This book was released on 2006-01-11 with total page 259 pages. Available in PDF, EPUB and Kindle. Book excerpt: Medical imaging has been transformed over the past 30 years by the advent of computerized tomography (CT), magnetic resonance imaging (MRI), and various advances in x-ray and ultrasonic techniques. An enabling force behind this progress has been the (so far) exponentially increasing power of computers, which has made it practical to explore fundamentally new approaches. In particular, what our group terms "model-based" modalities-which produce tissue property images from data using nonlinear, iterative numerical modeling techniques-have become increasingly feasible. Alternative Breast Imaging: Four Model-Based Approaches explores our research on four such modalities, particularly with regard to imaging of the breast: (1) MR elastography (MRE), (2) electrical impedance spectroscopy (EIS), (3) microwave imaging spectroscopy (MIS), and (4) near infrared spectroscopic imaging (NIS). Chapter 1 introduces the present state of breast imaging and discusses how our alternative modalities can contribute to the field. Chapter 2 looks at the computational common ground shared by all four modalities. Chapters 2 through 10 are devoted to the four modalities, with each modality being discussed first in a theory chapter and then in an implementation-and-results chapter. The eleventh and final chapter discusses statistical methods for image analysis in the context of these four alternative imaging modalities. Imaging for the detection of breast cancer is a particularly interesting and relevant application of the four imaging modalities discussed in this book. Breast cancer is an extremely common health problem for women; the National Cancer Institute estimates that one in eight US women will develop breast cancer at least once in her lifetime. Yet the efficacy of the standard (and notoriously uncomfortable) early-detection test, the x-ray mammogram, has been disputed of late, especially for younger women. Conditions are thus ripe for the development of affordable techniques that replace or complement mammography. The breast is both anatomically accessible and small enough that the computing power required to model it, is affordable.
Download or read book Breast Imaging written by Hiroshi Fujita and published by Springer. This book was released on 2014-06-23 with total page 787 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the refereed proceedings of the 12th International Workshop on Breast Imaging, IWDM 2014, held in Gifu City, Japan, in June/July 2014. The 24 revised full papers and 73 revised poster papers presented together with 6 invited talks were carefully reviewed and selected from 122 submissions. The papers are organized in topical sections on screening outcomes, ultrasound, breast density, imaging physics, CAD, tomosynthesis and ICT and image processing.
Download or read book Dual Modality Imaging System for Breast Cancer Research written by and published by . This book was released on 2004 with total page 44 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the 25-40% of the general female population with radiodense breast parenchyma, clinically occult lesions may be invisible in the screen-film mammogram. Even if suspicious masses are detected, determination of the benign or malignant nature of a mass is often impossible from the x-ray image. There is thus a need for diagnostic procedures that can noninvasively help characterize suspicious breast lesions. Scintimammography is an imaging technique that shows promise as an adjunct diagnostic tool in problem solving mammography, for monitoring recurrence after surgery, and in the assessment of multidrug-resistance. However, because clinical Anger cameras have only moderate spatial resolution and are difficult to position close to the breast, small lesions are difficult to detect. In addition, no direct means exists of correlating mammographic and scintigraphic information because of the significantly different shape of the breast in mammography (compressed) and scintimammography (prone, pendulant). We are developing an imaging system that overcomes these problems by combining digital x-ray mammography and gamma emission scintigraphy in a single, integrated system. The system is mounted on a standard upright mammography unit, and can easily be placed in a typical mammography room, providing accessibility even for small breast imaging clinics not associated with major medical centers.
Download or read book Developing Technologies for Early Detection of Breast Cancer written by National Research Council and published by National Academies Press. This book was released on 2000-08-06 with total page 24 pages. Available in PDF, EPUB and Kindle. Book excerpt: In November 1999, the Institute of Medicine, in consultation with the Commission on Life Sciences, the Commission on Physical Sciences, Mathematics, and Applications, and the Board on Science, Technology and Economic Policy launched a one year study on technologies for early detection of breast cancer. The committee was asked to examine technologies under development for early breast cancer detection, and to scrutinize the process of medical technology development, adoption, and dissemination. The committee is gathering information on these topics for its report in a number of ways, including two public workshops that bring in outside expertise. The first workshop on "Developing Technologies for Early Breast Cancer Detection" was held in Washington DC in February 2000. The content of the presentations at the workshop is summarized here. A second workshop, which will focus on the process of technology development and adoption, will be held in Washington, DC on June 19-20. A formal report on these topics, including conclusions and recommendations, will be prepared by the committee upon completion of the one-year study.
Download or read book Digital Mammography written by Gary J. Whitman and published by Cambridge University Press. This book was released on 2012-11-15 with total page 205 pages. Available in PDF, EPUB and Kindle. Book excerpt: Digital mammography has many advantages over film-screen mammography, including faster acquisition, easier storage and easier retrieval of images. Written by expert radiologists and physicists, Digital Mammography: A Practical Approach compares digital mammography to conventional film-screen mammography, reviews clinical cases and explores newer modalities. Key topics include: • Digital detectors • Monitors • Image acquisition • Image storage, retrieval and transfer • Image interpretation and efficacy • Artifacts • A comparison of commercially available systems • Mobile digital mammography. An image atlas and sections on digital tomosynthesis and computed tomography of the breast enhance the text. Digital Mammography: A Practical Approach melds the worlds of clinical radiology and physics in an easy-to-understand, practical resource. A valuable addition to the shelf of radiologists, radiologic technicians, practising medical physicists and mammography technologists; and any practitioners developing and expanding digital mammography programs.
