Download or read book Alpha Keto Acid Dehydrogenase Complexes written by M.S. Patel and published by Birkhäuser. This book was released on 2012-12-06 with total page 321 pages. Available in PDF, EPUB and Kindle. Book excerpt: Found in all organisms, the alpha-keto acid dehydrogenase complexes have central roles in cellular metabolism and are major sites of regulation. The understanding of the organization, function and regulation of these quintessential multienzyme complexes has been greatly advanced by studies employing molecular biology and biophysical techniques. Although these enzyme systems have some features in common, their diversity in fulfilling unique organism - or tissue - specific roles is truly amazing. These systems have medical importance in areas ranging from defects in regulation (linked to diabetes, heart disease, obesity, nutrition defects), to inherited diseases (inborn errors, maple syrup urine disease) to acquired immune diseases (primary biliary cirrhosis). This book brings together wide-ranging recent findings on the structure(function relationships, gene regulation, and genetic defects of the alpha-keto acid dehydrogenase complexes, namely the pyruvate dehydrogenase, alpha-ketoglutarate dehydrogenase and the branched-chain alpha-keto acid dehydrogenase complexes. A wide variety of experimental approaches together with new results presented in this book should serve as a resource for beginning to established investigators in the field as well as scientists who are interested in mitochondria, dehydrogenases, kinases, phosphatases, lipoic acid, thiamine pyrophosphate, and enzyme complexes.

Download or read book Chemistry and Biochemistry of the Amino Acids written by Graham Barrett and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 694 pages. Available in PDF, EPUB and Kindle. Book excerpt: Amino acids are featured in course syllabuses and in project and research work over a wide spectrum of subject areas in chemistry and biology. Chemists and biochemists using amino acids have many common needs when they turn to the literature for comprehensive information. Among these common interests, analytical studies, in particular, have undergone rapid development in recent years. All other chemical and biochemical aspects of amino acids - synthesis, properties and reactions, preparation of derivatives for use in peptide synthesis, racemization and other fundamental mechanistic knowledge - have been the subject of vigorous progress. This book offers a thorough treatment of all these developing areas, and is structured in the belief that biochemists, physiologists and others will profit from access to information on topics such as the physical chemistry of amino acid solutions, as well as from thorough coverage of amino acid metabolism, biosynthesis and enzyme inhibition; and that chemists will find relevant material in biological areas as well as in the analysis, synthesis and reactions of amino acids.

Download or read book Immunopharmacology and Inflammation written by Carlo Riccardi and published by Springer. This book was released on 2018-06-09 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive overview of the current research on inflammation and immunopharmacology, with particular attention to the use of anti-inflammatory drugs, this book discusses future trends in this area of pharmacological research. It addresses an audience with basic knowledge in the inflammatory process, immune system and pharmacology. The book meets the needs of graduate students, junior and senior researchers and is useful as a source of the most current information for those already working in these fields.

Download or read book Medical Biochemistry written by John W Baynes and published by Elsevier Health Sciences. This book was released on 2018-01-03 with total page 756 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now fully revised, this acclaimed textbook efficiently links basic biochemistry with the day-to-day practice of medicine. You will learn basic science concepts and see them illustrated by clinical cases that describe patients you will likely encounter in your clinical training. You will also learn about the use of laboratory tests to diagnose and monitor the most important conditions. Brought to you in a thorough yet accessible manner, this new edition of Medical Biochemistry highlights the latest developments in regulatory and molecular biology, signal transduction, biochemistry and biomarkers of chronic disease, and bioinformatics and the ‘–omics’. It highlights the most important global medical issues: diabetes mellitus, obesity and malnutrition, cancer and atherosclerotic cardiovascular disease, and addresses the role of nutrition and exercise in medicine. Featuring a team of expert contributors that includes investigators involved in cutting-edge research as well as experienced clinicians, this book offers a unique combination of research and clinical practice tailored to today’s integrated courses. Read organ-focused chapters addressing the biochemistry of the bone, kidney, liver, lungs and muscle; and system-focused ones addressing the biochemistry of the immune and endocrine systems, neurochemistry and neurotransmission, and cancer Featuring a team of expert contributors that includes investigators involved in cutting-edge research as well as experienced clinicians, this book offers a unique combination of research and clinical practice tailored to today's integrated courses. Read organ-focused chapters addressing the biochemistry of the bone, kidney, liver, lungs and muscle; and system-focused ones addressing the biochemistry of the immune and endocrine systems, neurochemistry and neurotransmission, and cancer

Download or read book Mechanistic Toxicology written by Urs A. Boelsterli and published by CRC Press. This book was released on 2007-03-23 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt: A thorough understanding of cellular and molecular mechanisms involved in the individual expression of toxic effects provides an important tool for assessment of human health risk. New aspects, major advances, and new areas in molecular and cellular biology and toxicology demand updated sources of information to elucidate the functional mechanics of human toxicology. Mechanistic Toxicology: The Molecular Basis of How Chemicals Disrupt Biological Targets, Second Edition retains the accessible format of the original to present the general principles that link xenobiotic-induced toxicity with the molecular pathways that underlie these toxic effects. Extensively illustrated, this book forms a conceptual bridge between multiple events at the molecular level and the determinants of toxicity at the physiological and cellular level. Specific examples of drugs, environmental pollutants, and other chemicals are carefully chosen to illustrate and highlight the fundamental mechanisms of toxicity at different toxicokinetic and toxicodynamic levels. The book includes references and review articles at the end of each chapter, as well as boxed text for relevant review information on biological, biochemical, molecular, and toxicological background. Linking molecular pathways to more general biomedical contexts, the author ensures that the reader is not lost in the details and instead receives a broad understanding of the processes underlying xenobiotic toxicity. New in the Second Edition Updated chapters Types of toxic responses Disruption of signal transduction by xenobiotics Disruption of mitochondrial function Novel mechanisms derived from systems toxicology

Download or read book Peptides written by Norbert Sewald and published by Wiley-VCH Verlag GmbH. This book was released on 2002-01-01 with total page 562 pages. Available in PDF, EPUB and Kindle. Book excerpt: Peptides play a decisive role in many physiological processes, whether as neurotransmitters, hormones or antibiotics. The rapid developments in peptide research over the past few decades make it almost impossible for newcomers to gain an overview. This means an easily comprehensible yet concise introduction is vital. This unique work covers all the important aspects of this wide-ranging field in one handy volume. On the basis of the fundamental chemical and structural properties of peptides, this reference runs the gamut from analysis, the occurrence and biological importance of peptides, via chemical, biochemical and genetic methods of peptide synthesis, right up to peptide libraries, peptide design and their role in drug research. Yet this book offers much more than a mere overview of the latest level of research. An encyclopedic appendix with valuable data on more than 500 biological relevant peptides and proteins, a comprehensive register and details of further literature references make this the ideal reference for all questions regarding peptide research. For newcomers and specialists alike. On the basis of the fundamental chemical and structural properties of peptides, this reference runs the gamut from analysis, the occurrence and biological importance of peptides.

Download or read book Dictionary of Medical Acronyms and Abbreviations written by Stanley Jablonski and published by Hanley & Belfus. This book was released on 2004-09 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: This dictionary lists acronyms and abbreviations occurring with a reasonable frequency in the literature of medicine and the health care professions. Abbreviations and acronyms are given in capital letters, with no punctuation, and with concise definitions. The beginning sections also include symbols, genetic symbols, and the Greek alphabet and symbols.

Download or read book First Aid for the USMLE Step 1 written by Vikas Bhushan and published by McGraw Hill Professional. This book was released on 2007-01-09 with total page 588 pages. Available in PDF, EPUB and Kindle. Book excerpt: The #1 Review for the USMLE Step 1 - written by students who aced the boards! 900+ must-know facts and mnemonics organized by organ systems and general principles 24 pages of color photos like those on the exam 100+ clinical vignettes Brand new Pathology chapter and totally revised Behavioral Science chapter The famous “First Aid Ratings” - 300+ medical test prep resources rated by students Updated exam preparation guide with advice from Step 1 veterans Strategies that maximize your study time and deliver the results you want

Download or read book Physical and Chemical Bases of Biological Information Transfer written by Julia Vassileva-Popova and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 443 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mathematical Approach and Models of Regulatory Mechanisms.- A New Mathematical Approach of Hormonal Regulatory Mechanisms during Growth.- The Aliosteric Model of Monod, Wyman and Changeux and the Phenomenon of Rising B/F-Curves in Hormone-Antibody Reactions.- Oxytocin Effect of the Depolarized Rat Uterus: A Mathematical Approach Using System Identification.- Method for Measuring the Development of Control Systems in Time.- Analytical Investigation of the Oscillatory Phenomenon in Hormone Regulation.- Substrate Concentration and Its Effect on the Application of the Law of Mass Action-A Brownian.

Download or read book Oxidative Damage to Plants written by Parvaiz Ahmad and published by Academic Press. This book was released on 2014-01-29 with total page 666 pages. Available in PDF, EPUB and Kindle. Book excerpt: With contributions that review research on this topic throughout the world, Oxidative Damage to Plants covers key areas of discovery, from the generation of reactive oxygen species (ROSs), their mechanisms, quenching of these ROSs through enzymatic and non-enzymatic antioxidants, and detailed aspects of such antioxidants as SOD and CAT. Environmental stress is responsible for the generation of oxidative stress, which causes oxidative damage to biomolecules and hence reduces crop yield. To cope up with these problems, scientists have to fully understand the generation of reactive oxygen species, its impact on plants and how plants will be able to withstand these stresses. - Provides invaluable information about the role of antioxidants in alleviating oxidative stress - Examines both the negative effects (senescence, impaired photosynthesis and necrosis) and positive effects (crucial role that superoxide plays against invading microbes) of ROS on plants - Features contributors from a variety of regions globally

Download or read book First Aid for the USMLE Step 1 2020 Thirtieth edition written by Tao Le and published by McGraw-Hill Education / Medical. This book was released on 2020-01-06 with total page 832 pages. Available in PDF, EPUB and Kindle. Book excerpt: Publisher's Note: Products purchased from Third Party sellers are not guaranteed by the publisher for quality, authenticity, or access to any online entitlements included with the product. EXCEL ON THE USMLE® STEP 1 WITH HELP FROM THE WORLD’S MOST POPULAR MEDICAL REVIEW BOOK! Trust First AidTM to help you score your highest on this high-stakes exam Written by students who excelled on the Step 1 exam and reviewed by top faculty for accuracy, this indispensable guide provides you with a blueprint of all the content you’re likely to find on the exam. Packed with insider advice for students from students, First Aid for the USMLE® Step 1 2020 will help maximize your study time. Features A complete framework for USMLE Step 1 preparation 1,300+ must-know topics with mnemonics to focus your study 1,000+ color photos and illustrations to help you visualize processes, disorders, and clinical findings Rapid Review section presents high-yield tables associating diseases with their clinical findings, treatments, and pathophysiology Updated every year to ensure all content is relevant and high-yield, reflecting the most current USMLE blueprint

Download or read book First Aid for the USMLE Step 1 2014 written by Tao Le and published by McGraw Hill Professional. This book was released on 2014-01-05 with total page 785 pages. Available in PDF, EPUB and Kindle. Book excerpt: The world's bestselling medical review book--with more than 1,250 frequently tested facts and mnemonics An unmatched collection of 1,250+ must-know facts and mnemonics provide a complete framework for your USMLE review Updates and new facts based on the largest student survey in First Aid history 350+ color clinical photographs with new arrows and captions New composite diagrams integrate complex concepts for easy memorization Updated rapid-review section for last-minute cramming Expanded faculty review process with nationally known USMLE instructors Free real-time updates and corrections at www.firstaidteam.com

Download or read book Basic Medical Sciences for MRCP written by Philippa J. Easterbrook and published by Churchill Livingstone. This book was released on 2005 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt: A revision book intended primarily for candidates sitting their MRCP Part 1 examination and which covers all the essential basic sciences. It focuses on the recurring themes which come up in the questions. The book also includes a chapter on clinical pharmacology (which alone accounts for up to 30% of the questions), looking at aspects of drug-induced disease and drug interactions. Finally there is a chapter on statistics and epidemiology which is rarely covered in other texts, but is often included in the exam. Despite the changes to the teaching of the undergraduate in medicine and the integration of the basic sciences with clinical education, the junior doctor, faced with postgraduate examinations, is always going to be poorly prepared for those increasingly important subjects. This book presents the essential information in the form of lists, tables, diagrams and flow charts.

Download or read book Analytical Determination of Nicotine and Related Compounds and their Metabolites written by J.W. Gorrod and published by Elsevier. This book was released on 1999-11-02 with total page 773 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides for the first time a single comprehensive source of information on the analytical chemistry of nicotine and related alkaloids. The editors have brought together scientists from academia and the tobacco industry to describe the state-of-the-art of the chemistry and analytical methods for measurement of nicotine. Both the scope and detail of the book are impressive. Chapters describe the history, pharmacology and toxicology of nicotine, the biosynthesis of nicotine and other alkaloids in the tobacco plant, the general chemistry of nicotine and the analytical methodologies that have been used to measure nicotine and related alkaloids in biological specimens, in tobacco and pharmaceutical products and in tobacco smoke. There is also a comprehensive review of the chemistry and toxicology of nicotine-derived nitrosamines, an important class of tobacco carcinogens.

Download or read book Diseases of the Newborn written by Alexander J. Schaffer and published by W.B. Saunders Company. This book was released on 1977 with total page 1388 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over 9000 English-language entries to medical terminology, with etymology given in Japanese and English. Entries include word in English; part of speech; Greek, Latin, or other roots; and elements of word.

Download or read book Epigenetics and Dermatology written by Qianjin Lu and published by Academic Press. This book was released on 2015-02-16 with total page 525 pages. Available in PDF, EPUB and Kindle. Book excerpt: Epigenetics and Dermatology explores the role of epigenetics in the pathogenesis of autoimmune-related skin diseases and skin cancer. Leading contributors cover common and uncommon skin conditions in which extensive epigenetic research has been done. They explain how environmental exposures (chemicals, drugs, sunlight, diet, stress, smoking, infection, etc.) in all stages of life (from a fetus in-utero to an elderly person) may result in epigenetic changes that lead to development of some skin diseases in life. They also discuss the possibilities of new and emergent epigenetic treatments which are gradually being adopted in management of various skin diseases. Chapters follow a conventional structure, covering fundamental biology of the disease condition, etiology and pathogenesis, diagnosis, commonly available treatments, and epigenetic therapy where applicable. Discusses the basic biology of skin diseases and skin cancers induced or aggravated by aberrant epigenetic changes Evaluates how to approach autoimmune-related skin diseases from a therapeutic perspective using the wealth of emergent epigenetic clinical trials Offers a coherent and structured table of contents with basic epigenetic biology followed by discussion of the spectrum of rheumatologic through neoplastic skin diseases, finally ending with a discourse on epigenetic therapy

Download or read book First Aid for the USMLE Step 1 2021 Thirty First Edition written by Tao Lee and published by . This book was released on 2021-02-09 with total page 46 pages. Available in PDF, EPUB and Kindle. Book excerpt: BUY NOW AND ENJOY FAST DELIVERY Publisher's Note: Products purchased from Third Party sellers are not guaranteed by the publisher for quality, authenticity, or access to any online entitlements included with the product. YOU NEED THIS UPDATED EDITION OF FIRST AID TO EXCEL ON THE REVISED USMLE(R) STEP 1! First Aid(TM) remains the most trusted name in USMLE(R) review―just ask any medical student! A complete framework for USMLE Step 1 preparation, annually updated with crowdsourced contributions from thousands of students Updated exam preparation advice for USMLE Step 1 pass/fail, Step 1 blueprint changes, and COVID-19 impacts New section on communication skills reflects the latest Step 1 content New focus on diversity, equity and inclusion incorporates race and ethnic considerations, as well as gender neutral terminology Nearly 1,400 must-know topics with mnemonics to focus your study 1,200+ color photos and illustration―170+ new or revised―help you visualize processes, disorders, and clinic findings Rapid Review section for efficient last-minute preparation Bonus material and real-time updates exclusively at FirstAidTeam.com