Download or read book A Bioinspired Gelatin Amorphous Calcium Phosphate Coating on Titanium Implant for Bone Regeneration written by Yanhuizhi Feng and published by . This book was released on 2023 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Calcium Phosphate Nanocoatings for Bone Regeneration written by Andy H. Choi and published by Springer Nature. This book was released on 2023-09-11 with total page 89 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides in-depth assessment on the latest clinical advances in multifunctional calcium phosphate nanocoatings and its influence on bone regeneration and early healing following implantation. A greater emphasis will be placed on the use of nanocomposite coatings to deliver biological materials such as mesenchymal stem cells, growth factors, bone morphogenetic and extracellular matrix proteins, and pharmaceutics such as simvastatin to improve and promote bone growth as well as reducing the timeframe needed for implant integration in both healthy and osteoporotic patients. The content of the book caters to clinical practitioners and researchers working in the field of biomaterials for bone regeneration.
Download or read book Thin Calcium Phosphate Coatings for Medical Implants written by Betty León and published by Springer Science & Business Media. This book was released on 2009-06-29 with total page 337 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents for the first time, the scattered novel results that have been achieved in very recent years in study on various thin calcium phosphate coatings produced by very diverse techniques. The comparison of thin calcium phosphate coatings with the thick plasma-sprayed ones is also included in the book. Readers will find a comprehensive book reviewing the state-of-the-art of the field with critical assessment of the achievements of the different preparation techniques.
Download or read book Characterization and Performance of Calcium Phosphate Coatings for Implants written by Emanuel Horowitz and published by ASTM International. This book was released on 1994 with total page 222 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Osteoconduction of Calcium Phosphate Thin Film on Porous surfaced Implants in Rabbit Tibiae written by Hung Quoc Nguyen and published by National Library of Canada = Bibliothèque nationale du Canada. This book was released on 1998 with total page 150 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Application of Calcium Phosphate Coating as Drug Delivery System for Orthopedic Implants written by Xiaohua Yu and published by . This book was released on 2011 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Calcium Orthophosphates written by Sergey V. Dorozhkin and published by CRC Press. This book was released on 2012-06-04 with total page 863 pages. Available in PDF, EPUB and Kindle. Book excerpt: Due to a great chemical similarity with the biological calcified tissues, many calcium orthophosphates possess remarkable biocompatibility and bioactivity. Materials scientists use this property extensively to construct artificial bone grafts that are either entirely made of or only surface-coated with the biologically relevant calcium orthophospha
Download or read book Smart Biomaterials written by Mitsuhiro Ebara and published by Springer. This book was released on 2014-05-28 with total page 380 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides comprehensive coverage of smart biomaterials and their potential applications, a field that is developing at a very rapid pace. Because smart biomaterials are an emerging class of biomaterials that respond to small changes in external stimuli with large discontinuous changes in their physical properties, they have been designed to act as an “on–off” switch for, among others, bio separation, immunoanalysis, drug delivery technologies, gene therapy, diagnostics, bio sensors and artificial muscles. After an introduction to the topic and the history of smart biomaterials, the author gives the reader an in-depth look at the properties, mechanics, and characterization of smart biomaterials including hydrogels, particles, assemblies, surfaces, fibers and conjugates. Information on the wide range of applications for these materials follows, including drug delivery, tissue engineering, diagnostics, biosensors, bio separation and actuators. In addition, recent advances in shape memory biomaterials as active components of medical devices are also presented.
Download or read book On the bone tissue response to titanium implants written by Lars Sennerby and published by . This book was released on 1991 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Extra t.p. with thesis statement inserted.
Download or read book Bone Tissue Engineering written by Jeffrey O. Hollinger and published by CRC Press. This book was released on 2004-10-14 with total page 500 pages. Available in PDF, EPUB and Kindle. Book excerpt: Focusing on bone biology, Bone Tissue Engineering integrates basic sciences with tissue engineering. It includes contributions from world-renowned researchers and clinicians who discuss key topics such as different models and approaches to bone tissue engineering, as well as exciting clinical applications for patients. Divided into four sections, t
Download or read book Advances in Calcium Phosphate Biomaterials written by Besim Ben-Nissan and published by . This book was released on 2014-05-31 with total page 572 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book 3D Printed Calcium Phosphate Scaffolds and Coatings on Titanium Alloys for Orthopedic Applications written by Dishary Banerjee and published by . This book was released on 2019 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: This study intends to understand the effects of dopants and natural medicinal compounds with osteogenic potential to improve bone formation leading to accelerated healing and improved implant performance.Doped hydroxyapatite coatings were developed on Ti alloys and were dip coated by acemannan to analyze its effects on the neo bone formation and chitosan to analyze the effects of polymer coating on the release kinetics. Chitosan leads to a controlled release of acemannan for 30 days. In vitro results demonstrate an enhanced osteoblast cell viability and proliferation by acemannan after 2 and 5 days of culture. Acemannan improved neo bone formation at early points in a rat distal femur defect model and chitosan enhanced mineralization. The bioavailability of acemannan was found to peak at ~25-30 days in a rat body.Increased systematic pH concentrations locally by the release of sodium bicarbonate diminished acidosis and alleviated malignancy. The same of dosage of doxorubicin inhibited both osteoblast and osteosarcoma cell attachment and viability whereas, sodium bicarbonate abated osteosarcoma cell proliferation. Sodium bicarbonate also inhibited osteoblast cell proliferation in the early time points, however, the cell viability increased after the initial burst release of the molecule. A coating of polycaprolactone (PCL) controlled the initial burst release of bicarbonate, which enhanced the osteoblast cell viability, but was capable of diminishing osteosarcoma cell proliferation.Calcium phosphate scaffolds with 3D-interconnected channels were fabricated to provide pathways for micronutrients and improved cell-material interactions through bioactive fixation. Gingerol, an antioxidant and anti-inflammatory molecule, enhances osteoblastic activity in addition to its anti-osteoclastic activity. However, due to its poor solubility and high intestinal liver metabolism, it showed limited oral efficacy in various preclinical and clinical studies. To enhance its bioavailability and to provide higher release, PCL and polyethylene glycol (PEG) were used as the polymeric system to enable continuous release of gingerol from the hydroxyapatite matrix for 25 days. Enhanced cell viability was observed with gingerol-PCL-PEG in static and dynamic culture conditions.Results show that local release of natural medicines and dopants has the potential for being used for wound healing and tissue regeneration applications in bone tissue engineering.
Download or read book Calcium Phosphate Coatings for Bone Regeneration written by Lan Yang and published by . This book was released on 2010 with total page 144 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Phytic Acid Calcium Hydroxide Composite Coating on Titanium Implants Promote Early Osseointegration written by Hao Zhang and published by . This book was released on 2017 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Abstract:Titanium surfaces have been constantly modified to improve bioactivity and osseointegration. In this study, we modified titanium surfaces through hydrothermal treatment with a mixed solution of phytic acid and calcium hydroxide, then evaluated their bioactive and osteogenic activities. In vitro tests, calcium-decorated titanium surface enhanced the cell adhesion, proliferation and osteogenic differentiation of human bone marrow mesenchymal stem cells (hBMSCs). In vivo tests, Micro- CT and histological evaluations indicated that the modified implants promoted new bone formation and osseointegration between the implants and the host bone. These findings provided evidence that this simple modification would be promising solution to improve bioactivity and osseointegration, which would be beneficial not only for titanium implants but also other implanted biomaterials.Background: Titanium (Ti) or titanium alloys coated with various bioactive calcium phosphates (CaPs), including hydroxyapatite (HA) and u03b2-tricalcium phosphate (u03b2-TCP), are considered as satisfactory implant materials. CaP coatings provide nanostructural or microstructuctural characteristics on titanium or titanium alloys, thereby increasing the adhesion of osteoblasts, which enhance the osseointegration and shorten the healing time.Aim: To prepare and evaluate the effect of calcium-containing chemical conversion coating on promoting new bone formation and early osseointegration in vivo.Material and methods: We designed and prepared a phytic acid/calcium hydroxide composite coating on the pure titanium implant (Ti-SLA-2/10) through hydrothermal treatment with a mixed solution of phytic acid (PA) and saturated calcium hydroxide solution [Ca (OH)2]. The pure titanium implant with a sandblasted/acid-etched (SLA) surface was used as the control group (Ti-SLA). The surface morphology, elemental composition, surface roughness, wettability, and calcium ion release were investigated separately. Twenty-four SLA and calcium-containing SLA implants were immediately inserted into the mandibles of twelve New Zealand white rabbits. The biological effects were evaluated by Micro-computed tomography (Micro-CT) analysis and histological evaluation after 1, 2, and 4 weeks of healing. Results: Phytic acid/calcium hydroxide composite coating with superior hydrophilicity were successfully prepared on titanium implants. The surface characteristics showed Ti-SLA-2/10 implants with multiple pits and craters can release calcium ions continuously. In vivo, the volume of new bone around the Ti-SLA-2/10 implants was significantly higher than that of the Ti-SLA implants, but more fibrous tissue was observed surround the Ti-SLA implants after 1 week of healing. The Ti-SLA-2/10 implants showed higher bone volume fraction (bone volume/total volume, BV/TV, %) than that of the Ti-SLA implants at each time points (p
Download or read book Biodegradable Systems in Tissue Engineering and Regenerative Medicine written by Rui L. Reis and published by CRC Press. This book was released on 2004-11-29 with total page 590 pages. Available in PDF, EPUB and Kindle. Book excerpt: Conventional materials technology has yielded clear improvements in regenerative medicine. Ideally, however, a replacement material should mimic the living tissue mechanically, chemically, biologically and functionally. The use of tissue-engineered products based on novel biodegradable polymeric systems will lead to dramatic improvements in health
Download or read book Stem Cell Biology and Tissue Engineering in Dental Sciences written by Ajaykumar Vishwakarma and published by Academic Press. This book was released on 2014-11-05 with total page 933 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stem Cell Biology and Tissue Engineering in Dental Sciences bridges the gap left by many tissue engineering and stem cell biology titles to highlight the significance of translational research in this field in the medical sciences. It compiles basic developmental biology with keen focus on cell and matrix biology, stem cells with relevance to tissue engineering biomaterials including nanotechnology and current applications in various disciplines of dental sciences; viz., periodontology, endodontics, oral & craniofacial surgery, dental implantology, orthodontics & dentofacial orthopedics, organ engineering and transplant medicine. In addition, it covers research ethics, laws and industrial pitfalls that are of particular importance for the future production of tissue constructs. Tissue Engineering is an interdisciplinary field of biomedical research, which combines life, engineering and materials sciences, to progress the maintenance, repair and replacement of diseased and damaged tissues. This ever-emerging area of research applies an understanding of normal tissue physiology to develop novel biomaterial, acellular and cell-based technologies for clinical and non-clinical applications. As evident in numerous medical disciplines, tissue engineering strategies are now being increasingly developed and evaluated as potential routine therapies for oral and craniofacial tissue repair and regeneration. Diligently covers all the aspects related to stem cell biology and tissue engineering in dental sciences: basic science, research, clinical application and commercialization Provides detailed descriptions of new, modern technologies, fabrication techniques employed in the fields of stem cells, biomaterials and tissue engineering research including details of latest advances in nanotechnology Includes a description of stem cell biology with details focused on oral and craniofacial stem cells and their potential research application throughout medicine Print book is available and black and white, and the ebook is in full color
Download or read book Advances in Calcium Phosphate Biomaterials written by Besim Ben-Nissan and published by Springer Science & Business. This book was released on 2014-04-17 with total page 559 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Calcium Phosphate Biomaterials presents a comprehensive, state-of-the-art review of the latest advances in developing calcium phosphate biomaterials and their applications in medicine. It covers the fundamental structures, synthesis methods, characterization methods, and the physical and chemical properties of calcium phosphate biomaterials, as well as the synthesis and properties of calcium phosphate-based biomaterials in regenerative medicine and their clinical applications. The book brings together these new concepts, mechanisms and methods in contributions by both young and “veteran” academics, clinicians, and researchers to forward the knowledge and expertise on calcium phosphate and related materials. Accordingly, the book not only covers the fundamentals but also open new avenues for meeting future challenges in research and clinical applications. Besim Ben-Nissan is a Professor of Chemistry and Forensic Science at the University of Technology, Sydney, Australia
