Download or read book 3D printed Microfluidics for Cancer Diagnostics and Selforganization of Benzoquinone Particle Flocks written by Tianqi Chen and published by . This book was released on 2021 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cancer is the second leading cause of death over the world. Early detection is the key to improve the patients' survival with more effective treatment and better recovery, compared to being diagnosed at a late cancer stage. So far, the mostly used and gold-standard cancer diagnostic method is the combination of imaging tests e.g., CT scan and pathological exams after the biopsy. Both techniques require specialized, bulky, and expensive instruments, trained personnel, and long report-waiting time with limited spatial resolution and sensitivity that can miss small lesion of a few cancer cells at the early stage and lead to false negative results. Testing of bodily fluids for cancer biomarkers represents a newer approach that can detect cancers at stages before tumors are measurable. Point-of-care (POC) testing and 3D-printed microfluidics miniaturize the testing, reduce costs and use simplified procedures, offering accessible diagnostic tools for early detection to people in both developed and developing countries. The first part of this thesis is devoted to the development of 3D-printed POC microfluidic immunoarrays for the sensitive detection of various cancer protein biomarkers in a low-cost, rapid, and user-friendly manner. Collective self-organization is a mysterious yet interesting phenomenon observed in many living systems, from flocks of birds organizing into different patterns in the sky to clusters of cells building tissues and organs in the human body. Similar motion can also be found in non-living systems composed of artificial active particles. Non-living systems can be used as simplified models to provide insights into self-organized motion in living systems. Nonlinear thermodynamic forces and flows have been proved to drive the self-organized motion, e.g., Marangoni effect and Marangoni flows. However, energy foraging behavior, a fundamental feature of living systems, has lacked clear demonstrations in non-living systems. The second part of this thesis investigates energy foraging behavior in a system of multiple benzoquinone particles, self-organizing into flocks and seeking for interfacial free energy at the air-water interface.

Download or read book Microfluidic Systems for Cancer Diagnosis written by Jose L. Garcia-Cordero and published by Springer Nature. This book was released on 2023-06-10 with total page 327 pages. Available in PDF, EPUB and Kindle. Book excerpt: This detailed volume explores recent developments in microfluidics technologies for cancer diagnosis and monitoring. The book is divided into two sections that delve into techniques for liquid biopsy for cancer diagnosis and platforms for precision oncology or personalized medicine in order to create effective patient avatars for testing anti-cancer drugs. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Microfluidic Systems for Cancer Diagnosis serves as an ideal guide that will be helpful to either replicate the construction of microfluidic devices specifically developed for cancer diagnosis or to catalyze development of new and better cancer diagnostic devices.

Download or read book Microfluidics and Biosensors in Cancer Research written by David Caballero and published by Springer Nature. This book was released on 2022-06-27 with total page 599 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book offers a comprehensive overview of the development and application of microfluidics and biosensors in cancer research, in particular, their applications in cancer modeling and theranostics. Over the last decades, considerable effort has been made to develop new technologies to improve the diagnosis and treatment of cancer. Microfluidics has proven to be a powerful tool for manipulating biological fluids with high precision and efficiency and has already been adopted by the pharmaceutical and biotechnology industries. With recent technological advances, particularly biosensors, microfluidic devices have increased their usefulness and importance in oncology and cancer research. The aim of this book is to bring together in a single volume all the knowledge and expertise required for the development and application of microfluidic systems and biosensors in cancer modeling and theranostics. It begins with a detailed introduction to the fundamental aspects of tumor biology, cancer biomarkers, biosensors and microfluidics. With this knowledge in mind, the following sections highlight important advances in developing and applying biosensors and microfluidic devices in cancer research at universities and in the industry. Strategies for identifying and evaluating potent disease biomarkers and developing biosensors and microfluidic devices for their detection are discussed in detail. Finally, the transfer of these technologies into the clinical environment for the diagnosis and treatment of cancer patients will be highlighted. By combining the recent advances made in the development and application of microfluidics and biosensors in cancer research in academia and clinics, this book will be useful literature for readers from a variety of backgrounds. It offers new visions of how this technology can influence daily life in hospitals and companies, improving research methodologies and the prognosis of cancer patients.

Download or read book Advanced Microfluidics Based Point of Care Diagnostics written by Raju Khan and published by CRC Press. This book was released on 2021-03-11 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a well-focused and comprehensive overview of novel technologies involved in advanced microfluidics based diagnosis via various types of prognostic and diagnostic biomarkers. This authors examine microfluidics based diagnosis in the biomedical field as an upcoming field with extensive applications. It provides a unique approach and comprehensive technology overview for diagnosis management towards early stages of various bioanalytes via cancer diagnostics diabetes, alzheimer disease, toxicity in food products, brain and retinal diseases, cardiovascular diseases, and bacterial infections etc. Thus, this book would encompass a combinatorial approach of medical science, engineering and biomedical technology. The authors provide a well-focused and comprehensive overview of novel technologies involved in advanced microfluidics based diagnosis via various types of prognostic and diagnostic biomarkers. Moreover, this book contains detailed description on the diagnosis of novel techniques. This book would serve as a guide for students, scientists, researchers, and microfluidics based point of care technologies via smart diagnostics and to plan future research in this valuable field.

Download or read book 3D Printed Microfluidic Devices written by Savas Tasoglu and published by MDPI. This book was released on 2019-01-10 with total page 213 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a printed edition of the Special Issue "3D Printed Microfluidic Devices" that was published in Micromachines

Download or read book 3D Printed Microfluidic Devices written by Tasoglu Savas and published by . This book was released on 2018 with total page 1 pages. Available in PDF, EPUB and Kindle. Book excerpt: 3D printing has revolutionized the microfabrication prototyping workflow over the past few years. With the recent improvements in 3D printing technologies, highly complex microfluidic devices can be fabricated via single-step, rapid, and cost-effective protocols as a promising alternative to the time consuming, costly and sophisticated traditional cleanroom fabrication. Microfluidic devices have enabled a wide range of biochemical and clinical applications, such as cancer screening, micro-physiological system engineering, high-throughput drug testing, and point-of-care diagnostics. Using 3D printing fabrication technologies, alteration of the design features is significantly easier than traditional fabrication, enabling agile iterative design and facilitating rapid prototyping. This can make microfluidic technology more accessible to researchers in various fields and accelerates innovation in the field of microfluidics. Accordingly, this Special Issue seeks to showcase research papers, short communications, and review articles that focus on novel methodological developments in 3D printing and its use for various biochemical and biomedical applications.

Download or read book Nanozymes From Rational Design to Biomedical Applications written by Kelong Fan and published by Frontiers Media SA. This book was released on 2021-05-31 with total page 151 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Modeling Phosphorus in the Environment written by David E. Radcliffe and published by CRC Press. This book was released on 2006-11-14 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: Despite advances in modeling, such as graphical user interfaces, the use of GIS layers, and databases for developing input files, the approaches to modeling phosphorus (P) have not changed since their initial development in the 1980s. Current understanding of P processes has evolved and this new information needs to be incorporated into the current models. Filling this need, Modeling Phosphorus in the Environment describes basic approaches to modeling P, how the current models implement these approaches, and ways to improve them. The book sets the scene with a review of general approaches to modeling runoff and erosion, P in runoff, leaching of P, stream processes that affect P, and an examination of the important issue of model uncertainty. It describes state-of-the-science watershed-scale P transport models including dynamic semi-disturbed models, models of intermediate complexity, and two lumped models. Phosphorus Indexes (PIs) represent one end of the modeling spectrum and the book takes a comprehensive look at PIs developed in each state, and illustrates some of the problems encountered when incorporating PIs into farm-scale manure management software. The book discusses monitoring data, which is critical for calibrating models, and concludes with suggestions for improving the modeling of P. From researching mechanisms to applying regulations, the uses of phosphorus models have increased as our knowledge of the effects of phosphorus in the environment has increased. Drawing on contributions from experts, the book gives you the tools to select the model that best fits your needs.

Download or read book Handbook of Forage and Rangeland Insects written by William O. Lamp and published by . This book was released on 2007 with total page 192 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Laboratory Guide for Conducting Soil Tests and Plant Analysis written by Jr., J. Benton Jones and published by CRC Press. This book was released on 2001-06-28 with total page 382 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the help of this guide, you can use obtained test results to evaluate the fertility status of soils and the nutrient element status of plants for crop production purposes. It serves as an instructional manual on the techniques used to perform chemical and physical characteristic tests on soils. Laboratory Guide for Conducting Soil Tests and Pl

Download or read book Advanced Strategies in Thin Film Engineering by Magnetron Sputtering written by Alberto Palmero and published by MDPI. This book was released on 2020-12-10 with total page 148 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent years have witnessed the flourishing of numerous novel strategies based on the magnetron sputtering technique aimed at the advanced engineering of thin films, such as HiPIMS, combined vacuum processes, the implementation of complex precursor gases or the inclusion of particle guns in the reactor, among others. At the forefront of these approaches, investigations focused on nanostructured coatings appear today as one of the priorities in many scientific and technological communities: The science behind them appears in most of the cases as a "terra incognita", fascinating both the fundamentalist, who imagines new concepts, and the experimenter, who is able to create and study new films with as of yet unprecedented performances. These scientific and technological challenges, along with the existence of numerous scientific issues that have yet to be clarified in classical magnetron sputtering depositions (e.g., process control and stability, nanostructuration mechanisms, connection between film morphology and properties or upscaling procedures from the laboratory to industrial scales) have motivated us to edit a specialized volume containing the state-of-the art that put together these innovative fundamental and applied research topics. These include, but are not limited to: • Nanostructure-related properties; • Atomistic processes during film growth; • Process control, process stability, and in situ diagnostics; • Fundamentals and applications of HiPIMS; • Thin film nanostructuration phenomena; • Tribological, anticorrosion, and mechanical properties; • Combined procedures based on the magnetron sputtering technique; • Industrial applications; • Devices.

Download or read book Second United States Microgravity Laboratory One Year Report written by M. Vlasse and published by . This book was released on 1998 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book ICoRD 13 written by Amaresh Chakrabarti and published by Springer Science & Business Media. This book was released on 2013-01-12 with total page 1404 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book showcases over 100 cutting-edge research papers from the 4th International Conference on Research into Design (ICoRD’13) – the largest in India in this area – written by eminent researchers from over 20 countries, on the design process, methods and tools, for supporting global product development (GPD). The special features of the book are the variety of insights into the GPD process, and the host of methods and tools at the cutting edge of all major areas of design research for its support. The main benefit of this book for researchers in engineering design and GPD are access to the latest quality research in this area; for practitioners and educators, it is exposure to an empirically validated suite of methods and tools that can be taught and practiced.

Download or read book Protein Structure Analysis written by Roza Maria Kamp and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 311 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Protein Structure Analysis - Preparation and Characterization" is a compilation of practical approaches to the structural analysis of proteins and peptides. Here, about 20 authors describe and comment on techniques for sensitive protein purification and analysis. These methods are used worldwide in biochemical and biotechnical research currently being carried out in pharmaceu tical and biomedical laboratories or protein sequencing facilities. The chapters have been written by scientists with extensive ex perience in these fields, and the practical parts are well documen ted so that the reader should be able to easily reproduce the described techniques. The methods compiled in this book were demonstrated in student courses and in the EMBO Practical Course on "Microsequence Analysis of Proteins" held in Berlin September 10-15, 1995. The topics also derived from a FEBS Workshop, held in Halkidiki, Thessaloniki, Greece, in April, 1995. Most of the authors participated in these courses as lecturers and tutors and made these courses extremely lively and successful. Since polypeptides greatly vary depending on their specific structure and function, strategies for their structural analysis must for the most part be adapted to each individual protein. Therefore, advantages and limitations of the experimen tal approaches are discussed here critically, so that the reader becomes familiar with problems that might be encountered.

Download or read book Chaplin s Limelight and the Music Hall Tradition written by Frank Scheide and published by McFarland. This book was released on 2006-10-12 with total page 229 pages. Available in PDF, EPUB and Kindle. Book excerpt: Charles Spencer Chaplin was a stage performer before he was a filmmaker, and it was in English music hall that he learned the rudiments of his art. The last film he made in the United States, Limelight, was a tribute to the music hall days of his youth. As a parallel to Chaplin's past, the film was set in 1914, the year he left the stage for a Hollywood career. This collection of essays examines Limelight and the history of English music hall. Featuring contributions from the world's top Chaplin and music hall historians, as well as previously unpublished interviews with collaborators who worked on Limelight, the book offers new insight into one of Chaplin's most important pictures and the British form of entertainment that inspired it. Essays consider how and why Chaplin made Limelight, other artists who came out of English music hall, and the film's international appeal, among other topics. The book is filled with rare photographs, many published for the first time, sourced from the Chaplin archives and the private collections of other performers and co-stars.

Download or read book Human Capital and Economic Growth written by Andreas Savvides and published by Stanford University Press. This book was released on 2008-10-10 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an in-depth investigation of the link between human capital and economic growth. The authors take an innovative approach, examining the determinants of economic growth through a historical overview of the concept of human capital. The text fosters a deep understanding of the connection between human capital and economic growth through the exploration of different theoretical approaches, a review of the literature, and the application of nonlinear estimation techniques to a comprehensive data set. The authors discuss nonparametric econometric techniques and their application to estimating nonlinearities—which has emerged as one of the most salient features of empirical work in modeling the human capital-growth relationship, and the process of economic growth in general. By delving into the topic from theoretical and empirical standpoints, this book offers an insightful new view that will be extremely useful for scholars, students, and policy makers.

Download or read book Research Into Design written by Amaresh Chakrabarti and published by Research Publishing Service. This book was released on 2011 with total page 118 pages. Available in PDF, EPUB and Kindle. Book excerpt: