Download or read book 32P Postlabeling for DNA Adduct Determination in Plants written by FA. Ireland and published by . This book was released on 1991 with total page 12 pages. Available in PDF, EPUB and Kindle. Book excerpt: Barley (Hordeum vulgare L.) and Australian saltbush (Atriplex semibaccata)plants and deoxyribonucleic acid (DNA) isolated from barley were exposed to the known carcinogen/mutagen, N-methyl-N-nitrosourea (MNU). DNA was isolated, digested to a mixture of deoxyribonucleoside 5'-monophosphates, postlabeled with [?-32P] ATP, and separated on polyethyleneimine (PEI)-cellulose thin layer chromatography plates. Autoradiograms of the chromatograms showed the presence of normal DNA constituents as well as additional spots not present on autoradiograms of untreated DNA. These data suggest that DNA adducts are formed in growing plants and in plant DNA exposed to a carcinogen. In addition, a discussion of the 32P-postlabeling procedure and similarities and differences encountered using plants and plant DNA are addressed.
Download or read book 32P postlabelling Analysis of Complex DNA Adducts in Human Tissues written by Ke Yang and published by . This book was released on 1998 with total page 59 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Plants for Toxicity Assessment written by Wun-cheng Wang and published by ASTM International. This book was released on 1991 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: The First Symposium on Use of Plants for Toxicity Assessment was held in Atlanta, Georgia, on April 19-20, 1989. This publication contains 29 refereed papers divided into six groups: Regulatory Perspectives, Comparative Toxicology, Plants and Xenobiotic Uptake, Plants and Air Pollution, General Phytotoxicology, and New Approaches. The 2nd Symposium on Use of Plants for Toxicity Assessment was held in San Francisco, California, on April 23-24, 1990. This publication contains 35 refereed papers divided into six groups: Regulatory Perspectives, Applications of Plant Bioassays/Photosynthesis, Xenobiotic Uptake by Plants, General Phytotoxicology, Biochemical and Genetic Applications, and New Approaches.
Download or read book 32P postlabeling Analysis of Aromatic DNA Adducts in Hemopoietic Tissues and Blood of the Mummichog Fundulus Heteroclitus written by Wendy L. Rose and published by . This book was released on 1999 with total page 180 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Environmental Health Perspectives written by and published by . This book was released on 1993 with total page 636 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Special Reports written by Robert Snyder and published by . This book was released on 1993 with total page 804 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Biomarkers written by and published by . This book was released on 1996 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Methods for Genetic Risk Assessment written by David Brusick and published by CRC Press. This book was released on 1994-01-11 with total page 274 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genetic disease contributes to a major portion of our health care costs. While most of the human genetic burden is transmitted from generation to generation, environmental chemicals capable of reacting with germ cell DNA could produce new mutations, resulting in an even greater genetic liability for the next generation. The potential impact of environmental mutagens on the health and viability of other living things is important to consider as well. Methods for Genetic Risk Assessment features contributions from international experts to provide a comprehensive review of the current status of genetic risk assessment. You'll learn about various methods and strategies for when and how to conduct genetic risk assessments on human populations. You will also learn about the potential effects of environmental genotoxins on nonhuman organisms. Topics considered include:
Download or read book Molecular Environmental Biology written by Seymour J. Garte and published by CRC Press. This book was released on 1993-11-23 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular Environmental Biology is the first book to illustrate molecular biological approaches to major issues in environmental biology. International experts have contributed representative chapters that cover how molecular methods and concepts apply to wildlife management, ecology, pollution control and remediation, and environmental health. Specific topics discussed include the use of molecular techniques in the population biology of wild animals and in the management of fisheries, bioremediation, cloning and characterization of the genes responsible for degradation of PCBs and related environmental pollutants, molecular analysis of aromatic hydrocarbon degradation by soil bacteria, and molecular biological techniques in assessing environmental damage to natural habitats. The book also explores how new molecular approaches can be applied to human disease etiology and epidemiology. Topics discussed in this area include an introduction to molecular epidemiology, the uses of molecular biological markers in cancer risk assessment, specific environmental carcinogens found in foods, measuring DNA adducts and mutation frequencies to assess environmental toxic exposures and effect, and using the extent of gene inducibility as a dosimeter of toxic exposure. This book will interest researchers and students in all fields of environmental biology and environmental medicine. Readers will find information on new techniques and applications of established molecular methodology that will stimulate new research ideas, collaborations, and progress. Researchers will now have a chance to make rapid progress on environmental questions that were previously not even open for exploration.
Download or read book Molecular Dosimetry and Human Cancer written by Paul L. Skipper and published by CRC Press. This book was released on 1991-05-21 with total page 492 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides readers with a broad view of the field of molecular dosimetry by discussing its origins, underlying concepts, the wide range of approaches to making the measurements and applications for the results. Specific topics include the direct assessment of human carcinogens and assessment of low level risks, molecular epidemiology, validation of molecular epidemiologic methods, quantitative analysis of DNA adducts, the application of fluorescence to analysis of genotoxicity, exposure control versus risk assessment, genetic testing in the workplace, and medical screening for carcinogenesis.
Download or read book Toxicological Evaluation of Chemical Interactions written by and published by . This book was released on 1994 with total page 704 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Cumulated Index Medicus written by and published by . This book was released on 1997 with total page 1850 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Child Health written by and published by . This book was released on 1995 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Estrogens in the Environment III written by and published by . This book was released on 1993 with total page 958 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Comprehensive Toxicology written by and published by Elsevier. This book was released on 2017-12-01 with total page 8639 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comprehensive Toxicology, Third Edition, Fifteen Volume Set discusses chemical effects on biological systems, with a focus on understanding the mechanisms by which chemicals induce adverse health effects. Organized by organ system, this comprehensive reference work addresses the toxicological effects of chemicals on the immune system, the hematopoietic system, cardiovascular system, respiratory system, hepatic toxicology, renal toxicology, gastrointestinal toxicology, reproductive and endocrine toxicology, neuro and behavioral toxicology, developmental toxicology and carcinogenesis, also including critical sections that cover the general principles of toxicology, cellular and molecular toxicology, biotransformation and toxicology testing and evaluation. Each section is examined in state-of-the-art chapters written by domain experts, providing key information to support the investigations of researchers across the medical, veterinary, food, environment and chemical research industries, and national and international regulatory agencies. Thoroughly revised and expanded to 15 volumes that include the latest advances in research, and uniquely organized by organ system for ease of reference and diagnosis, this new edition is an essential reference for researchers of toxicology. Organized to cover both the fundamental principles of toxicology and unique aspects of major organ systems Thoroughly revised to include the latest advances in the toxicological effects of chemicals on the immune system Features additional coverage throughout and a new volume on toxicology of the hematopoietic system Presents in-depth, comprehensive coverage from an international author base of domain experts
Download or read book Molecular Biology of the Toxic Response written by Alvaro Puga and published by CRC Press. This book was released on 1998-10-14 with total page 604 pages. Available in PDF, EPUB and Kindle. Book excerpt: Encouraging the incorporation of molecular biology techniques into the experimental approach to various toxicological problems, the format of the book is two-staged. Each chapter first introduces how various molecular techniques can be successfully applied to solving a specific toxicology question and proceeds to describe the techniques themselves. Also included is a discussion of the benefits and limitations of these techniques . This book will prove of value to practising researchers, but also to graduate students dealing with conceptual issues relating to molecular toxicology.
Download or read book Annual Report written by National Cancer Institute (U.S.). Division of Cancer Etiology and published by . This book was released on 1990 with total page 538 pages. Available in PDF, EPUB and Kindle. Book excerpt:
